Supplement reference
Vitamin B6 (P5P)
A source-linked reference on Vitamin B6 (P5P), evidence, safety and product identity. Sources checked 6 September 2026.
Source and review status
Published sources checked
Sources checked on: 6 September 2026
Qualified clinical review: Pending. This page has not been clinically reviewed.
About this source check
AI-assisted editorial source checking covers the cited material and its stated limits. It is not a systematic review, verification of a supplied product, or clinical sign-off.
Editorial role: InfoAddict. Last material change: 6 September 2026. Next source review: 6 March 2027.
Ingredient and preparation
P5P is pyridoxal-5-phosphate, an active vitamin B6 form used in some supplements.
Sources: National Institutes of Health, Office of Dietary Supplements
Evidence and limits
NIH describes vitamin B6 functions and cautions that high supplemental intakes over time can cause severe nerve damage. The reviewed source does not establish P5P as superior for mood, energy or neuropathy.
Sources: National Institutes of Health, Office of Dietary Supplements
Safety and a useful record
Total vitamin B6 can accumulate across products. Review all labels and nerve symptoms with a healthcare professional rather than escalating use.
Sources: National Institutes of Health, Office of Dietary Supplements, National Center for Complementary and Integrative Health
Record the form, total daily B6 from every product and any sensory symptoms.
Sources: National Center for Complementary and Integrative Health
Published sources
- Vitamin B6: Fact Sheet for Consumers
National Institutes of Health, Office of Dietary Supplements. Current NIH ODS reference; accessed 6 September 2026.
Supports: Vitamin B6 functions, excess-risk and interaction context. It does not establish P5P-specific benefit.
- Safe Use of Complementary Health Products and Practices
National Center for Complementary and Integrative Health. Current NCCIH reference; accessed 6 September 2026.
Supports: General safety, interaction and contamination context. It does not establish ingredient-specific benefit.
Change history
| Date | Change | Clinical-review status |
|---|---|---|
| 6 September 2026 | Source-linked reference published | Pending |
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