Supplement reference
Phosphatidylserine (PS)
A source-linked reference on Phosphatidylserine (PS), evidence, safety and product identity. Sources checked 6 September 2026.
Source and review status
Published sources checked
Sources checked on: 6 September 2026
Qualified clinical review: Pending. This page has not been clinically reviewed.
About this source check
AI-assisted editorial source checking covers the cited material and its stated limits. It is not a systematic review, verification of a supplied product, or clinical sign-off.
Editorial role: InfoAddict. Last material change: 6 September 2026. Next source review: 6 March 2027.
Ingredient and preparation
Phosphatidylserine is a phospholipid; supplement products can differ in source and amount.
Sources: National Library of Medicine, PubMed
Evidence and limits
The cited systematic review covered 11 controlled studies of citicoline or phosphatidylserine-containing treatments in mental disorders. Findings were heterogeneous and inconsistent, with high risk of bias, so it does not establish a cognitive-enhancer effect for a retail product.
Sources: National Library of Medicine, PubMed
Safety and a useful record
Product source, medicine context and the population studied matter. Do not infer suitability from a cognitive-performance label.
Sources: National Library of Medicine, PubMed, National Center for Complementary and Integrative Health
Record source material, amount on label, other cognitive or sleep changes and the outcome being followed.
Sources: National Center for Complementary and Integrative Health
Published sources
- The Impact of Citicoline/Phosphatidylserine Supplementation on Cognitive Performance and Executive Functions in Mental Disorders: A Systematic Review of Controlled Trials
National Library of Medicine, PubMed. Published September 2026; accessed 6 September 2026.
Supports: Eleven controlled studies across mental-disorder populations; findings were heterogeneous and inconsistent, with high risk of bias.
- Safe Use of Complementary Health Products and Practices
National Center for Complementary and Integrative Health. Current NCCIH reference; accessed 6 September 2026.
Supports: General safety, interaction and contamination context. It does not establish ingredient-specific benefit.
Change history
| Date | Change | Clinical-review status |
|---|---|---|
| 6 September 2026 | Source-linked reference published | Pending |
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