Supplement reference

NR (Nicotinamide Riboside)

A source-linked reference on NR (Nicotinamide Riboside), evidence, safety and product identity. Sources checked 6 September 2026.

Source and review status

Published sources checked

Sources checked on: 6 September 2026

Qualified clinical review: Pending. This page has not been clinically reviewed.

About this source check

AI-assisted editorial source checking covers the cited material and its stated limits. It is not a systematic review, verification of a supplied product, or clinical sign-off.

Editorial role: InfoAddict. Last material change: 6 September 2026. Next source review: 6 March 2027.

Ingredient and preparation

Nicotinamide riboside is a nicotinamide-related compound sold in products that often reference NAD metabolism.

Sources: National Library of Medicine, PubMed

Evidence and limits

The cited review pooled human trials of NMN and NR in older adults and found muscle-function evidence inconclusive. Changes in NAD-related biomarkers do not by themselves establish a patient-important outcome.

Sources: National Library of Medicine, PubMed

Safety and a useful record

The safety and interaction discussion depends on the product, health history and other medicines. Do not generalise from laboratory or short-term findings.

Sources: National Library of Medicine, PubMed, National Center for Complementary and Integrative Health

Record the product identity, stated outcome and any relevant tests with their laboratory range.

Sources: National Center for Complementary and Integrative Health

Published sources

  1. The Effect of Nicotinamide Mononucleotide and Riboside on Skeletal Muscle Mass and Function: A Systematic Review and Meta-Analysis

    National Library of Medicine, PubMed. Published 2025; accessed 6 September 2026.

    Supports: Human NMN/NR trials in older adults; pooled evidence for muscle-function outcomes was inconclusive.

  2. Safe Use of Complementary Health Products and Practices

    National Center for Complementary and Integrative Health. Current NCCIH reference; accessed 6 September 2026.

    Supports: General safety, interaction and contamination context. It does not establish ingredient-specific benefit.

Change history

DateChangeClinical-review status
6 September 2026Source-linked reference publishedPending

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