Supplement reference
L-Citrulline
A source-linked reference on L-Citrulline, evidence, safety and product identity. Sources checked 6 September 2026.
Source and review status
Published sources checked
Sources checked on: 6 September 2026
Qualified clinical review: Pending. This page has not been clinically reviewed.
About this source check
AI-assisted editorial source checking covers the cited material and its stated limits. It is not a systematic review, verification of a supplied product, or clinical sign-off.
Editorial role: InfoAddict. Last material change: 6 September 2026. Next source review: 6 March 2027.
Ingredient and preparation
L-citrulline is an amino acid. It is distinct from citrulline malate, a combination label that may not match studies of citrulline alone.
Sources: National Library of Medicine, PubMed
Evidence and limits
A 2022 systematic review found no pooled positive effect on its included aerobic-performance outcomes. That does not answer every exercise question or establish a benefit for other outcomes.
Sources: National Library of Medicine, PubMed
Safety and a useful record
The review is not a safety or dosing instruction. Review medicines and health conditions with a suitable professional before changing use.
Sources: National Library of Medicine, PubMed, National Center for Complementary and Integrative Health
Record whether the label is L-citrulline alone or a mixed product, plus the outcome and training context.
Sources: National Center for Complementary and Integrative Health
Published sources
- Effects of Citrulline Supplementation on Different Aerobic Exercise Performance Outcomes: A Systematic Review and Meta-Analysis
National Library of Medicine, PubMed. Published 2022; accessed 6 September 2026.
Supports: No pooled positive effect on included aerobic performance outcomes; not a dosing source.
- Safe Use of Complementary Health Products and Practices
National Center for Complementary and Integrative Health. Current NCCIH reference; accessed 6 September 2026.
Supports: General safety, interaction and contamination context. It does not establish ingredient-specific benefit.
Change history
| Date | Change | Clinical-review status |
|---|---|---|
| 6 September 2026 | Source-linked reference published | Pending |
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