Supplement reference
HMB (Beta-Hydroxy Beta-Methylbutyrate)
A sourced reference on HMB (Beta-Hydroxy Beta-Methylbutyrate) identity, evidence limits and safety context.
Source and review status
Published sources checked
Sources checked on: 6 September 2026
Qualified clinical review: Pending. This page has not been clinically reviewed.
About this source check
AI-assisted editorial source checking covers the cited material and its stated limits. It is not a systematic review, verification of a supplied product, or clinical sign-off.
Editorial role: InfoAddict. Last material change: 6 September 2026. Next source review: 6 March 2027.
Identity and product form
HMB is beta-hydroxy beta-methylbutyrate, a metabolite of leucine. The free-acid and calcium-salt forms should be distinguished on the label.
Sources: National Institutes of Health, Office of Dietary Supplements
What the reviewed evidence can and cannot show
NIH’s exercise-performance fact sheet discusses HMB research in selected exercise and body-composition contexts. It does not establish a treatment for frailty, injury or muscle loss.
Sources: National Institutes of Health, Office of Dietary Supplements
Safety and limits
Record the exact form and combination ingredients. Muscle weakness, unexplained weight loss or functional decline need clinical assessment rather than supplement self-management.
Sources: National Institutes of Health, Office of Dietary Supplements
Published sources
- ExerciseAndAthleticPerformance Fact Sheet for Health Professionals
National Institutes of Health, Office of Dietary Supplements. Current NIH fact sheet; accessed 6 September 2026.
Supports: Nutrient or performance-research context and relevant safety limits.
Change history
| Date | Change | Clinical-review status |
|---|---|---|
| 6 September 2026 | Source-linked reference published | Pending |
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