Supplement reference
Folate (Methylfolate)
A sourced reference on Folate (Methylfolate) identity, evidence limits and safety context.
Source and review status
Published sources checked
Sources checked on: 6 September 2026
Qualified clinical review: Pending. This page has not been clinically reviewed.
About this source check
AI-assisted editorial source checking covers the cited material and its stated limits. It is not a systematic review, verification of a supplied product, or clinical sign-off.
Editorial role: InfoAddict. Last material change: 6 September 2026. Next source review: 6 March 2027.
Identity and product form
Folate is vitamin B9; methylfolate is a supplemental form. Folate from food and folic acid or other supplemental forms have different labelling and metabolism considerations.
Sources: National Institutes of Health, Office of Dietary Supplements
What the reviewed evidence can and cannot show
NIH describes folate’s role in DNA and cell division and provides pregnancy-related public-health context. It does not make methylfolate a general treatment for mood, methylation or fatigue.
Sources: National Institutes of Health, Office of Dietary Supplements
Safety and limits
NIH notes that high supplemental folate can mask vitamin B12 deficiency. Pregnancy planning, anaemia symptoms, seizure medicines and other medicines need professional assessment.
Sources: National Institutes of Health, Office of Dietary Supplements
Published sources
- Folate Fact Sheet for Health Professionals
National Institutes of Health, Office of Dietary Supplements. Current NIH fact sheet; accessed 6 September 2026.
Supports: Nutrient or performance-research context and relevant safety limits.
Change history
| Date | Change | Clinical-review status |
|---|---|---|
| 6 September 2026 | Source-linked reference published | Pending |
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