Supplement reference

CoQ10 (Ubiquinol)

A sourced reference on CoQ10 (Ubiquinol) identity, evidence limits and safety context.

Source and review status

Published sources checked

Sources checked on: 6 September 2026

Qualified clinical review: Pending. This page has not been clinically reviewed.

About this source check

AI-assisted editorial source checking covers the cited material and its stated limits. It is not a systematic review, verification of a supplied product, or clinical sign-off.

Editorial role: InfoAddict. Last material change: 6 September 2026. Next source review: 6 March 2027.

What it is

Ubiquinol is the reduced form of coenzyme Q10. It should be distinguished from ubiquinone and from a general energy claim.

Sources: National Library of Medicine, PubMed

What the cited evidence shows

A 2026 meta-analysis examined CoQ10 trials for depressive symptoms and fatigue in people with depression or underlying illness. Its population and outcomes do not establish benefit for healthy people, every CoQ10 form, cardiovascular disease or statin symptoms.

Sources: National Library of Medicine, PubMed

Limits and safety context

This reference does not provide a treatment or medicine-adjustment plan.

Sources: National Library of Medicine, PubMed

Published sources

  1. Coenzyme Q10 and depressive symptoms/fatigue: systematic review and meta-analysis

    National Library of Medicine, PubMed. 2026; accessed 6 September 2026.

    Supports: Trials in people with depression or underlying illness; not evidence for ubiquinol in healthy people or every CoQ10 form.

Change history

DateChangeClinical-review status
6 September 2026Source-linked reference publishedPending

Keep a private record

UpgradeYourself lets you keep private records of routines and observations you choose to discuss with a qualified health professional. This reference does not recommend starting, stopping or changing an item.